公立大学法人 奈良県立医科大学へ

公立大学法人 奈良県立医科大学薬理学教室
教室紹介　薬理学教育　教室実績






誌上発表

-欧文原著-
  1. Izawa Y, Yoshizumi M, Ishizawa K, Fujita Y, Kondo S, Kagami S, Kawazoe K,
    Tsuchiya K, Tomita S, Tamaki T.
    Big mitogen-activated protein kinase 1 (BMK1)/extracellular signal regulated kinase 5 (ERK5) is involved in platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell migration.
    Hypertens. Res. 30, (11) 1107-1117 (2007)
  2. Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat　J, Yoshizumi M, Yan C, Abe JI, Berk BC.
    Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells.
    Biochem. Biophys. Res. Commun. 370, (1) 159-163 (2008)
  3. Nakayama H, Hamada M, Fujikake N, Nagai Y, Zhao J, Hatano O, Shimoke K, Isosaki M, Yoshizumi M, Ikeuchi T.
    ER stress is the initial response to polyglutamine toxicity in PC12 cells.
    Biochem. Biophys. Res. Commun. 370, (1) 159-163 (2008)
  4. Nakayama H, Zhao J, Amany El-Fakharany, Isosaki M, Satoh H, Kyotani Y,
    Yoshizumi M.
    Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells.
    Clin. Exp. Pharmacol. Physiol.36, (12) 1183-1185 (2009)
  5. Urushihara M, Takamatsu M, Shimizu M, Kondo S, Kinoshita Y, Suga K, Kitamura
    A, Matsuura S, Yoshizumi M, Tamaki T, Kawachi H, Kagami S.
    ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.
    Am. J. Physiol. Renal Physiol. 298, (1) F167-F176 (2010)
  6. Kurobe H, Urata M, Ueno M, Ueki M, OnoS, Izawa-Ishizawa Y, Fukuhara Y, Lei Y, Ripen AM, Kanbara T, Aihara K, Ishizawa K, Akaike M, Gonzalez FJ, Tamaki T, Takahama Y, Yoshizumi M, Kitagawa T, Tomita S.
    Role of HIF-1α in T cells as a negative regulator in development of vascular remodeling.
    Arterioscler. Thromb. Vasc. Biol. 30, (2) 210-217 (2010)
  7. Liu G, Miyata K, Hitomi H, Yao L, Sun GP, Suzaki Y, Hosomi N, Kiyomoto H, Nakano D, Tamaki T, Yoshizumi M, Nishiyama A.
    Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation.
    J. Hypertens. 28, (3) 536-542 (2010)
  8. Yoji Kyotani, Jing Zhao, Sayuko Tomita, Hitoshi Nakayama, Minoru Isosaki, Masayuki Uno, Masanori Yoshizumi.
    Olmesartan inhibits angiotensin II-induced migration of vascular smooth muscle cells through Src and MAP kinase pathways.
    J. Pharmacol. Sci. 113, (2) 161-168（2010)
  9. Jing Zhao, Yoji Kyotani, Satoyasu Itoh, Hitoshi Nakayama, Minoru Isosaki, Masanori Yoshizumi.
    Big Mitogen-activated Protein Kinase 1 Protects Cultured Rat Aortic Smooth Muscle Cells from Oxidative Damage.
    J. Pharmacol. Sci. 116, (2) 173-180 (2011)
  10. Fujimoto E, Yoshizumi M, Kanbara T, Kurobe H, Motoki T, Sugano M, Nakayama T, Kitaichi T, Kitagawa T. Functional restoration of endothelial cells of the cryopreserved heart valve.
    Gen. Thorac. Cardiovasc. Surg. 59, (3) 169-174 (2011)
  11. Minoru Isosaki, Hitoshi Nakayama, Yoji Kyotani, Jing Zhao, Sayuko Tomita, Hiroyasu Satoh, Masanori Yoshizumi.
    Prevention of the wortmannnin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents.
    Pharmacol. Rep. 63, 733-739 (2011)
  12. Komatsubara AT, Asano T, Tsumoto H, Shimizu K, Nishiuchi T, Yoshizumi M,
    Ozawa K.
    Proteomic analysis of S-nitrosylation induced by 1-methyl-4-
    phenylpyridinium (MPP+).
    Proteome Sci. 10(1), 74-80 (2012)
  13. Ozawa K , Komatsubara AT, Nishimura Y, Sawada T, Kawafune H, Tsumoto H, Tsuji
    Y, Zhao J, Kyotani Y, Tanaka T, Takahashi R, Yoshizumi M.
    S-nitrosylation regulates mitochondrial quality control via activation of
    parkin.
    Scientific Reports 3, 2202 (2013)
  14. Yoji Kyotani, Hiroyo Ota, Asako Itaya-Hironaka, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Jing Zhao, Kentaro Ozawa, Kosuke Nagayama, Satoyasu Ito, Shin Takasawa, Hiroshi Kimura, Masayuki Uno, Masanori Yoshizumi.
    Intermittent hypoxia induces the proliferation of rat vascular smooth muscle cell with the increases in epidermal growth factor family and erbB2 receptor.
    Exp. Cell Res. 319(19), 3042-3050（2013)
-欧文総説-

  1. Masanori Yoshizumi, Yasuo Matsumura.
    Forum minireview, Pharmacology in health foods: Preface
    J. Pharmacol. Sci. 115, (4) 459-460 (2011)
  2. Keisuke Ishizawa, Masanori Yoshizumi, Yoshichika Kawai, Junji Terao, Yoshitaka Kihira, Yasumasa Ikeda, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki.
    Forum minireview, Pharmacology in health foods: Metabolism of quercetin in vivo and its protective effect against arteriosclerosis.
    J. Pharmacol. Sci. 115, (4) 466-470 (2011)
  3. Masanori Yoshizumi, Yoji Kyotani, Jing Zhao, Kosuke Nagayama, Satoyasu Ito, Yuichi Tsuji, Kentaro Ozawa
    The role of big mitogen-activated protein kinase 1 (BMK1)/ extracellular signal-regulated kinase 5 (ERK5) in the pathogenesis and progression of atherosclerosis.
    J. Pharmacol. Sci. 120, (4) 259-263 (2012)
-和文原著-

  1. 趙　晶、京谷陽司、伊藤都裕、長山功祐、小澤健太郎、吉栖正典
    アンジオテンシンＩＩ刺激による血管平滑筋細胞の遊走に対するSrc阻害とＭＡＰキナーゼ阻害効果の比較
    奈良医学雑誌　63, (1,2) 25-35 (2012)
-和文総説-

  1. 京谷陽司、趙　晶、吉栖正典
    最近の話題「サプリメントのＥＢＭ」
    日本薬理学雑誌　133, (5) 297　(2009)
  2. 吉栖正典
    「メタボリックシンドローム対策の実際」
    チーム医療で取り組むメタボッリクシンドローム対策
    循環器plus　10, (12) 10-12　(2010)
  3. 京谷陽司、趙　晶、長山功佑、伊藤都裕、小澤健太郎、吉栖正典
    閉塞性睡眠時無呼吸と心血管病
    血管　35, (2) 69-74 (2012)





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